Galectin-3

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Lectin, galactoside-binding, soluble, 3, also known as LGALS3, is a human gene.[1] In melanocytic cells LGALS3 gene expression may be regulated by MITF[2].



Interactions

LGALS3 has been shown to interact with LGALS3BP.[3][4][5]

See also


  1. "Entrez Gene: LGALS3 lectin, galactoside-binding, soluble, 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=3958. 
  2. Hoek KS, Schlegel NC, Eichhoff OM, et al. (2008). "Novel MITF targets identified using a two-step DNA microarray strategy". Pigment Cell Melanoma Res. 21 (6): 665–76. doi:10.1111/j.1755-148X.2008.00505.x. PMID 19067971. 
  3. Rosenberg, I; Cherayil B J, Isselbacher K J, Pillai S (Oct. 1991). "Mac-2-binding glycoproteins. Putative ligands for a cytosolic beta-galactoside lectin". J. Biol. Chem. (UNITED STATES) 266 (28): 18731-6. ISSN 0021-9258. PMID 1917996. 
  4. Koths, K; Taylor E, Halenbeck R, Casipit C, Wang A (Jul. 1993). "Cloning and characterization of a human Mac-2-binding protein, a new member of the superfamily defined by the macrophage scavenger receptor cysteine-rich domain". J. Biol. Chem. (UNITED STATES) 268 (19): 14245-9. ISSN 0021-9258. PMID 8390986. 
  5. Tinari, N; Kuwabara I, Huflejt M E, Shen P F, Iacobelli S, Liu F T (Jan. 2001). "Glycoprotein 90K/MAC-2BP interacts with galectin-1 and mediates galectin-1-induced cell aggregation". Int. J. Cancer (UNITED STATES) 91 (2): 167-72. ISSN 0020-7136. PMID 11146440. 


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